Structure Information
Structure

Compound Identification

SMILES

CCC(C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]1C[C@@H](C\C=C(C)\C(O[C@H]3C[C@H](OC)[C@@H](NC(=O)CCNC(=O)CCCCCNC(=O)CCCC[C@@H]4SCC5NC(=O)NC45)[C@H](C)O3)[C@@H](C)\C=C\C=C3/COC4[C@H](O[Si](C)(C)C(C)(C)C)C(C)=C[C@@H](C(=O)O1)[C@]34O)O2

InChIKey

InChIKey=ZAKLZPNOHPSEEG-CGMGKQDASA-N

Formula

C66H107N5O14SSi

Mass

1254.75

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Taxonomic Classification

Taxonomy Tree

Kingdom

Organic compounds

Superclass

Phenylpropanoids and polyketides

Class

Macrolides and analogues

Subclass

Milbemycins

Intermediate Tree Nodes

Not available

Direct Parent

Milbemycins

Alternative Parents

Molecular Framework

Aliphatic heteropolycyclic compounds

Substituents

Milbemycin - Biotin_derivative - Beta amino acid or derivatives - Thienoimidazolidine - Ketal - Fatty amide - Imidazolidinone - N-acyl-amine - Oxane - Fatty acyl - Imidazolidine - Oxolane - Thiophene - Thiolane - Trialkylheterosilane - Tertiary alcohol - Carboxamide group - Carboxylic acid ester - Lactone - Silyl ether - Urea - Secondary carboxylic acid amide - Organoheterosilane - Oxacycle - Azacycle - Organic metalloid salt - Carboxylic acid derivative - Dialkyl ether - Ether - Acetal - Organoheterocyclic compound - Dialkylthioether - Monocarboxylic acid or derivatives - Thioether - Organic oxygen compound - Alcohol - Carbonyl group - Organopnictogen compound - Organic oxide - Organic metalloid moeity - Organonitrogen compound - Organooxygen compound - Organic nitrogen compound - Organosilicon compound - Hydrocarbon derivative - Aliphatic heteropolycyclic compound

Description

This compound belongs to the class of organic compounds known as milbemycins. These are a group of macrolides with a structure containing a 16-membered lactone ring fused to a 1,7-dioxaspiroundecane ring system and to either a benzofuran (or hydrogenated derivative thereof). In some cases (e.g. Milbemycin E), the tetrahydrofuranyl ring is missing. Milbemycins can be o-glycosylated at C13 to form Avermectins. Milbemycins are produced by Streptomyces species.

External Descriptors

Not available

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