Compound Identification
SMILES
CCC(C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]1C[C@@H](C\C=C(C)\C(O[C@H]3C[C@H](OC)[C@@H](NC(=O)CCNC(=O)CCCCCNC(=O)CCCC[C@@H]4SCC5NC(=O)NC45)[C@H](C)O3)[C@@H](C)\C=C\C=C3/COC4[C@H](O[Si](C)(C)C(C)(C)C)C(C)=C[C@@H](C(=O)O1)[C@]34O)O2
InChIKey
InChIKey=ZAKLZPNOHPSEEG-CGMGKQDASA-N
Formula
C66H107N5O14SSi
Mass
1254.75
Taxonomic Classification
Taxonomy Tree
-
Kingdom
Organic compounds
-
Superclass
Phenylpropanoids and polyketides
-
Class
Macrolides and analogues
- Subclass Milbemycins
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Class
Macrolides and analogues
-
Superclass
Phenylpropanoids and polyketides
Kingdom
Organic compounds
Superclass
Phenylpropanoids and polyketides
Class
Macrolides and analogues
Subclass
Milbemycins
Intermediate Tree Nodes
Not available
Direct Parent
Milbemycins
Alternative Parents
Biotin and derivatives Beta amino acids and derivatives Thienoimidazolidines Ketals Imidazolidinones N-acyl amines Oxanes Trialkylheterosilanes Thiophenes Thiolanes Tertiary alcohols Oxolanes Carboxylic acid esters Ureas Silyl ethers Lactones Secondary carboxylic acid amides Dialkylthioethers Monocarboxylic acids and derivatives Dialkyl ethers Organic metalloid salts Oxacyclic compounds Azacyclic compounds Hydrocarbon derivatives Carbonyl compounds Organic oxides Organonitrogen compounds Organopnictogen compounds
Molecular Framework
Aliphatic heteropolycyclic compounds
Substituents
Milbemycin - Biotin_derivative - Beta amino acid or derivatives - Thienoimidazolidine - Ketal - Fatty amide - Imidazolidinone - N-acyl-amine - Oxane - Fatty acyl - Imidazolidine - Oxolane - Thiophene - Thiolane - Trialkylheterosilane - Tertiary alcohol - Carboxamide group - Carboxylic acid ester - Lactone - Silyl ether - Urea - Secondary carboxylic acid amide - Organoheterosilane - Oxacycle - Azacycle - Organic metalloid salt - Carboxylic acid derivative - Dialkyl ether - Ether - Acetal - Organoheterocyclic compound - Dialkylthioether - Monocarboxylic acid or derivatives - Thioether - Organic oxygen compound - Alcohol - Carbonyl group - Organopnictogen compound - Organic oxide - Organic metalloid moeity - Organonitrogen compound - Organooxygen compound - Organic nitrogen compound - Organosilicon compound - Hydrocarbon derivative - Aliphatic heteropolycyclic compound
Description
This compound belongs to the class of organic compounds known as milbemycins. These are a group of macrolides with a structure containing a 16-membered lactone ring fused to a 1,7-dioxaspiroundecane ring system and to either a benzofuran (or hydrogenated derivative thereof). In some cases (e.g. Milbemycin E), the tetrahydrofuranyl ring is missing. Milbemycins can be o-glycosylated at C13 to form Avermectins. Milbemycins are produced by Streptomyces species.
External Descriptors
Not available