Structure Information
Structure

Compound Identification

SMILES

O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12.CCC1=C2C=C(OC(=O)N3CCC(CC3)N3CCCCC3)C=CC2=NC2=C1CN1C2=CC2=C(COC(=O)[C@]2(O)CC)C1=O

InChIKey

InChIKey=SERKAJNXBGMDQB-WAQYZQTGSA-N

Formula

C46H48N6O10

Mass

844.922

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Taxonomic Classification

Taxonomy Tree

Kingdom

Organic compounds

Superclass

Alkaloids and derivatives

Class

Camptothecins

Subclass

Not available

Intermediate Tree Nodes

Not available

Direct Parent

Camptothecins

Alternative Parents

Molecular Framework

Not available

Substituents

Camptothecin - Phthalimide - Alpha-amino acid or derivatives - Isoindolone - Pyranopyridine - Quinoline - Piperidinecarboxylic acid - Isoindoline - Isoindole or derivatives - Isoindole - Piperidinedione - 4-aminopiperidine - Piperidinone - Delta-lactam - Pyridinone - Pyridine - Carboxylic acid imide, n-substituted - Piperidine - Benzenoid - Carboxylic acid imide - Carboxylic acid imide, n-unsubstituted - Heteroaromatic compound - Dicarboximide - Tertiary alcohol - Carbamic acid ester - Amino acid or derivatives - Carboxylic acid ester - Tertiary aliphatic amine - Tertiary amine - Lactam - Lactone - Organoheterocyclic compound - Azacycle - Oxacycle - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Amine - Hydrocarbon derivative - Organic nitrogen compound - Carbonyl group - Organic oxide - Alcohol - Organooxygen compound - Organic oxygen compound - Organonitrogen compound - Aromatic heteropolycyclic compound

Description

This compound belongs to the class of organic compounds known as camptothecins. These are heterocyclic compounds comprising a planar pentacyclic ring structure, that includes a pyrrolo[3,4-beta]-quinoline moiety (rings A, B and C), conjugated pyridone moiety (ring D) and one chiral center at position 20 within the alpha-hydroxy lactone ring with (S) configuration (the E-ring).

External Descriptors

Not available

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