Compound Identification
SMILES
C[C@H]1CC[C@]2(C[C@@H]3C[C@@H](C\C=C(C)\[C@H](O)[C@@H](C)\C=C\C=C4/CO[C@@H]5\C(=N/O[Si](C)(C)C(C)(C)C)C(C)=C[C@@H](C(=O)O3)[C@]45O)O2)O[C@@H]1C1CCCCC1
InChIKey
InChIKey=NKLJQOONZLWSLJ-NNTPKQHGSA-N
Formula
C42H65NO8Si
Mass
740.066
Taxonomic Classification
Taxonomy Tree
-
Kingdom
Organic compounds
-
Superclass
Phenylpropanoids and polyketides
-
Class
Macrolides and analogues
- Subclass Milbemycins
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Class
Macrolides and analogues
-
Superclass
Phenylpropanoids and polyketides
Kingdom
Organic compounds
Superclass
Phenylpropanoids and polyketides
Class
Macrolides and analogues
Subclass
Milbemycins
Intermediate Tree Nodes
Not available
Direct Parent
Milbemycins
Alternative Parents
Ketals Oxanes Oxolanes Trialkylheterosilanes Tertiary alcohols Secondary alcohols Lactones Carboxylic acid esters Oxacyclic compounds Organic metalloid salts Monocarboxylic acids and derivatives Dialkyl ethers Carbonyl compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework
Aliphatic heteropolycyclic compounds
Substituents
Milbemycin - Ketal - Oxane - Trialkylheterosilane - Oxolane - Tertiary alcohol - Carboxylic acid ester - Lactone - Secondary alcohol - Acetal - Carboxylic acid derivative - Dialkyl ether - Ether - Monocarboxylic acid or derivatives - Organoheterosilane - Oxacycle - Organoheterocyclic compound - Organic metalloid salt - Organic metalloid moeity - Alcohol - Organopnictogen compound - Organonitrogen compound - Organooxygen compound - Organic nitrogen compound - Organic oxide - Hydrocarbon derivative - Organosilicon compound - Carbonyl group - Organic oxygen compound - Aliphatic heteropolycyclic compound
Description
This compound belongs to the class of organic compounds known as milbemycins. These are a group of macrolides with a structure containing a 16-membered lactone ring fused to a 1,7-dioxaspiroundecane ring system and to either a benzofuran (or hydrogenated derivative thereof). In some cases (e.g. Milbemycin E), the tetrahydrofuranyl ring is missing. Milbemycins can be o-glycosylated at C13 to form Avermectins. Milbemycins are produced by Streptomyces species.
External Descriptors
Not available