Structure Information
Structure

Compound Identification

SMILES

CCCCCN1C=NC2=CC=CC3=C2C1=C1CN2C(=CC4=C(COC(=O)[C@@]4(CC)OC(=O)CC[C@@H](NC(=O)[C@@H](N)CC4=CC=CC=C4)C(O)=O)C2=O)C1=N3

InChIKey

InChIKey=LVOLUFBCKMJJSM-LKVULEDUSA-N

Formula

C40H42N6O8

Mass

734.81

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Taxonomic Classification

Taxonomy Tree

Kingdom

Organic compounds

Superclass

Alkaloids and derivatives

Class

Camptothecins

Subclass

Not available

Intermediate Tree Nodes

Not available

Direct Parent

Camptothecins

Alternative Parents

Molecular Framework

Aromatic heteropolycyclic compounds

Substituents

Camptothecin - Alpha peptide - Alpha-dipeptide - Phenylalanine or derivatives - Glutamic acid or derivatives - N-acyl-alpha amino acid or derivatives - N-acyl-alpha-amino acid - Alpha-amino acid amide - Quinazoline - Quinoline - Diazanaphthalene - Pyranopyridine - Pyridopyrimidine - Alpha-amino acid or derivatives - Amphetamine or derivatives - Tricarboxylic acid or derivatives - Fatty acid ester - Aralkylamine - Pyridinone - Monocyclic benzene moiety - Fatty amide - Fatty acyl - Pyridine - Benzenoid - Pyrimidine - Heteroaromatic compound - Secondary carboxylic acid amide - Amino acid or derivatives - Amino acid - Carboxamide group - Carboxylic acid ester - Lactam - Lactone - Organoheterocyclic compound - Azacycle - Carboxylic acid derivative - Oxacycle - Carboxylic acid - Organic oxide - Organonitrogen compound - Carbonyl group - Organooxygen compound - Organic nitrogen compound - Amine - Primary amine - Hydrocarbon derivative - Organic oxygen compound - Primary aliphatic amine - Aromatic heteropolycyclic compound

Description

This compound belongs to the class of organic compounds known as camptothecins. These are heterocyclic compounds comprising a planar pentacyclic ring structure, that includes a pyrrolo[3,4-beta]-quinoline moiety (rings A, B and C), conjugated pyridone moiety (ring D) and one chiral center at position 20 within the alpha-hydroxy lactone ring with (S) configuration (the E-ring).

External Descriptors

Not available

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