Structure Information
Structure

Compound Identification

SMILES

CC[C@@]1(OC(=O)CN)C(=O)OCC2=C1C=C1N(CC3=C1N=C1C=C4OCOC4=C(N)C1=C3)C2=O.C[C@H]1O[C@@H](O[C@@H]2C[C@@H]3O[C@@](O)(C[C@H](O)[C@H]3C(O)=O)C[C@@H](O)C[C@@H](O)CC[C@H](O)[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@@H](C)[C@H](O)[C@@H](C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\2)[C@@H](O)[C@@H](N)[C@@H]1O

InChIKey

InChIKey=JNGUFMPEEVFWKF-CMKUINFXSA-N

Formula

C70H93N5O24

Mass

1388.525

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Taxonomic Classification

Taxonomy Tree

Kingdom

Organic compounds

Superclass

Alkaloids and derivatives

Class

Camptothecins

Subclass

Not available

Intermediate Tree Nodes

Not available

Direct Parent

Camptothecins

Alternative Parents

Molecular Framework

Not available

Substituents

Camptothecin - Aminoglycoside core - Alpha-amino acid ester - Macrolide - Hexose monosaccharide - Aminoquinoline - Glycosyl compound - O-glycosyl compound - Alpha-amino acid or derivatives - Pyranopyridine - Quinoline - Benzodioxole - Amino saccharide - Beta-hydroxy acid - Pyridinone - Benzenoid - Dicarboxylic acid or derivatives - Hydroxy acid - Monosaccharide - Oxane - Primary aromatic amine - Pyridine - Heteroaromatic compound - Amino acid or derivatives - 1,2-aminoalcohol - Secondary alcohol - Carboxylic acid ester - Lactone - Lactam - Amino acid - Hemiacetal - Acetal - Polyol - Oxacycle - Carboxylic acid derivative - Carboxylic acid - Organoheterocyclic compound - Azacycle - Organic oxide - Alcohol - Organic nitrogen compound - Organopnictogen compound - Organic oxygen compound - Carbonyl group - Primary amine - Primary aliphatic amine - Organonitrogen compound - Amine - Organooxygen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound

Description

This compound belongs to the class of organic compounds known as camptothecins. These are heterocyclic compounds comprising a planar pentacyclic ring structure, that includes a pyrrolo[3,4-beta]-quinoline moiety (rings A, B and C), conjugated pyridone moiety (ring D) and one chiral center at position 20 within the alpha-hydroxy lactone ring with (S) configuration (the E-ring).

External Descriptors

Not available

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